WELCOME TO SANTA MONICA CLINICAL TRIALS
Santa Monica Clinical Trials is a private clinical research site located in Los Angeles, California. Our Investigators have over 20 years of experience and are engaged in numerous phase II-IV clinical research trials, including drug and medical device studies. Participation does not require proof of medical insurance. All trials are conducted under FDA guidance and regulations.
If you or a loved one suffers from one of these disorders, take the next step and contact a member of our study team today! No medical insurance needed. Compensation for time & travel may be available upon inquiry.
CURRENT TRIALS
PRADER-WILLI SYNDROME
Prader-Willi Syndrome (PWS) is a congenital syndrome that affects many systems of the body. Common early signs of PWS include muscle weakness, feeding difficulties, and behavioral disturbances. Patients may also experience excessive daytime sleepiness (EDS), making it difficult to perform everyday activities and negatively affecting their mood. The purpose of this study is to evaluate the efficacy and safety of the study medication on daytime sleepiness in those with Prader-Willi Syndrome.
NARCOLEPSY
Narcolepsy is a chronic neurological disorder that affects the brain's ability to regulate sleep-wake cycles. Those with narcolepsy experience excessive daytime sleepiness despite feeling well-rested upon waking. Individuals might have frequent, uncontrollable bouts of sleep. Depending on the type of narcolepsy, symptoms may also include sudden muscle weakness causing patients to go limp. This study will explore the efficacy and safety of an oral study medication in promoting wakefulness in those with narcolepsy type 1 (NT1) or narcolepsy type 2 (NT2).
IDIOPATHIC HYPERSOMNIA
Idiopathic hypersomnia (IH) is a rare neurological disorder which is characterized primarily by excessive sleep and excessive daytime sleepiness. This study will look at safety and efficacy of the oral investigational drug in promoting wakefulness for those with idiopathic hypersomnia.
SLEEP APNEA
Obstructive Sleep Apnea (OSA) is a common and serious sleep disorder in which breathing is repeatedly interrupted during sleep. OSA occurs when the airway collapses as you breathe in. This can cause breathing to be paused from several seconds to over a minute.
While many people use continuous positive airway pressure (CPAP) machines to manage their OSA, these systems can be cumbersome and awkward for some. The LunAIRo study involves an investigational oral medication for people who have OSA. The investigational medication will be taken daily at bedtime.
SLEEP DISTURBANCES IN INDIVIDUALS WITH AUTISM SPECTRUM DISORDER
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is associated with persistent deficits in social communication, restricted/repetitive behaviors, among other symptoms. Sleep disruption in individuals with ASD is higher than in healthy controls with a documented prevalence of up to 80%. The purpose of this study is to evaluate the effectiveness and safety of the study medication on sleep in individuals with autism spectrum disorder.
MOTION SICKNESS
Motion sickness is a common condition affecting about 30% of the population. Common symptoms of motion sickness include nausea, vomiting, stomach awareness, pallor, headache, sweating, dizziness, a sensation of warmth and drowsiness. The purpose of the study is to evaluate the effectiveness of an investigational drug on symptoms associated with motion sickness and to assess the safety of the investigational drug.
DELAYED SLEEP-WAKE PHASE DISORDER
Delayed sleep–wake phase disorder (DSWPD) is a chronic dysregulation of a person's circadian rhythm (biological clock), compared to those of the general population and societal norms. People with DSWPD generally fall asleep some hours after midnight and have difficulty waking up in the morning. However, they find it very difficult to wake up in time for a typical school or work day. If they are allowed to follow their own schedules, e.g. sleeping from 4:00 am to 1:00 pm, their sleep is improved and they may not experience excessive daytime sleepiness. The purpose of this study is to evaluate the efficacy and safety of an investigational medication compared to placebo for this condition.
